1. Ivan Djuricic, Mašinski fakultet Univerziteta u Beogradu, Serbia
2. Jovana Šakota-Rosić, Mašinski fakultet Univerziteta u Beogradu, Serbia
3. Ivana Stanković (Mileusnić), Mašinski fakultet Univerziteta u Beogradu, 4. Jelena Munćan, Mašinski fakultet Univerziteta u Beogradu, Serbia
5. Boris Kosić, Mašinski fakultet Univerziteta u Beogradu, Serbia
6. Dušan Šarac, Univeristy of Belgrade, Faculty of Mechanical Engineering, Serbia
7. Lidija Matija, Mašinski fakultet Univerziteta u Beogradu, Serbia
Immediately after being placed on the eye, contact lenses are coated with a protein layer and most proteins attach strongly to the material, with typically less than 50% being removed by conventional care regimens. The deposition of certain proteins to contact lenses has shown to increase the risk of microbial cell attachment to the lens material, and is also associated with inflammatory complications [1].
The purpose of this study was the classification between the groups of worn and new -unused soft contact lenses of different materials and produced by different manufacturers, using near infrared spectra of the contact lenses. Application of multivariate analysis on the spectral data showed that it is possible to distinguish the two groups, based on the absorbance of water molecules involved in protein hydration (1425nm, [2]). It can be concluded that NIR spectroscopy could be used for studying of protein depositions on soft contact lenses in their natural biological conditions, and furthermore prove insight into the mechanism of adsorption.
This exploratory study showed the potential of near infrared spectroscopy for non-invasive, chemical free detection of protein deposits on contact lenses, which could in future allow for simple and rapid characterization of contact lens materials from the aspects of protein adsorption and thus provide simple solution for the choice of optimal biomaterial formula for soft contact lenses development and production.
[1] Luensmann, D., & Jones, L. (2012). Protein deposition on contact lenses: The past, the present, and the future. Contact Lens and Anterior Eye
[2] Tsenkova, R. (2009). Introduction: Aquaphotomics: dynamic spectroscopy of aqueous and biological systems describes peculiarities of water. Journal of Near Infrared Spectroscopy, 17(1), 303.
Ključne reči :
Tematska oblast:
SIMPOZIJUM B - Biomaterijali i nanomedicina
Datum:
14.06.2015.
Contemporary Materials 2015 - Savremeni Materijali
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