1. Jelena Marić, JZU Bolnica "Sveti Vračevi" Bijeljina,
Republic of Srpska, Bosnia and Herzegovina
2. Zlatko Maksimović, ZU Specijalistički centar "MaxMedic" Bijeljina,
Republic of Srpska, Bosnia and Herzegovina
Ultrasound contrast agents (UCAs) have revolutionized diagnostic imaging by enhancing ultrasound signal quality through the use of gas-filled microbubbles or emerging submicron particles. These agents provide real-time, radiation-free imaging and are especially advantageous for patients with renal impairment. Second-generation UCAs, composed of inert gases like perfluorocarbons and stabilized by biocompatible shells, offer improved stability and imaging duration. Clinically, UCAs are widely used in cardiovascular and abdominal imaging, notably for echocardiography and liver lesion characterization, with expanding roles in vascular, oncologic, and pediatric applications. Their intravascular confinement, excellent safety profile, and non-nephrotoxic nature make them suitable for a broad patient population. Molecularly targeted microbubbles and novel nanodroplets further enhance diagnostic specificity and enable theranostic applications, including targeted imaging and drug delivery. While current clinical use is limited to microbubbles, ongoing research into submicron agents and molecular targeting suggests a promising future for UCAs in both diagnostics and therapy
Ključne reči :
Tematska oblast:
SIMPOZIJUM B - Biomaterijali i nanomedicina
Datum:
06.08.2025.
Contemporary Materials 2025 - Savremeni Materijali
Datoteka uz rad