1. Stela Taci, University Hospital Centre , Albania
2. Sonela Xinxo, Institute of Public Health, Tirane, ALBANIA, Albania
3. Edite Sadiku , University Hospital Centre , Albania
4. Jovan Basho , University Hospital Centre , Albania
Background: Hepatitis C virus (HCV) is one of the major causes of chronic hepatitis. It is important to know the genotypes of HCV in the decision of the HCV related chronic hepatitis therapy.
Aim: To identify the distribution of the HCV genotypes among patients who got antiviral therapy for HCV.
Methods. The study was carried out at the University Hospital Centre “Mother Teresa” in Tirana, Albania from 2006 until 2015. All patient who have been identify with HCV and met the criteria for treatment with antiretroviral have been included in the study. The data on the genotype of HCV and sex was collected for each of the participant. The chi square was used to identify if there is any difference on HCV genotypes by sex.
Results: In total, 265 patients have been included in the study. One hundred and forty patients ( 52.8%) are male. The most prevalent genotype is type 1b with 55 % of cases, followed genotype 2a/2c with 18.5 % and genotype 2 with 13.2 %. The other genotype of HCV are encountered for about 15 % of the patients.
When this distribution is compared by age there is significant difference by sex in distribution of genotype 2a/2c ( 24 % among women vs 13.5 among men, p<0.05) and other types ( 7.2% among women vs 18 % among men, p<0.05). There is not identified any significant difference regarding the prevalence of genotype 1b by sex ( p>0.05).
Conlusion: The most prevalent HCV genotype among patient under treatment is 1b followed by genotype 2a/2c and 2. The genotype 1b is prevalent equally by sex meanwhile genotype 2a/2c is significantly most prevalent among women.
Ključne reči :
Tematska oblast:
Ostalo
Datum:
15.07.2016.
XI Savjetovanje hemičara, tehnologa i ekologa Republike Srpske
