1. Marija Pergal, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, Serbia
2. Vanja Vojnović, Centar za mikroelektronske tehnologije, Institut za hemiju, tehnologiju i metalurgiju, Univerzitet u, Serbia
3. Ivan Pešić, Centar za mikroelektronske tehnologije, Institut za hemiju, tehnologiju i metalurgiju, Univerzitet u, Serbia
4. Milena Rašljić Rafajilović, Centar za mikroelektronske tehnologije, Institut za hemiju, tehnologiju i metalurgiju, Univerzitet u, Serbia
5. Stefan Ilić, Centar za mikroelektronske tehnologije, Institut za hemiju, tehnologiju i metalurgiju, Univerzitet u, Serbia
6. Teodora Vićentić, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, Serbia
7. Gordana Tovilović-Kovačević, Institut za biološka istraživanja „Siniša Stanković”, Univerzitet u Beogradu, Bulevar despota Stefana, Serbia
8. Marko Spasenović, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, Serbia
Flexible, biocompatible, and highly sensitive piezoresistive sensors based on MXene (Ti₃C₂Tₓ) and laser-induced graphene (LIG) represent an essential advancement for wearable electronics in biomedical applications. Polyurethanes (PUs) based on poly(dimethylsiloxane) (PDMS) segments have gained significant attention as substrates for sensors due to their excellent biocompatibility, superior elasticity, mechanical strength, and chemical stability. This lecture discusses innovative strategies in developing flexible strain and pulse sensors using MXene and LIG deposited on biocompatible PU substrates. PU-based composites were prepared via a two-step polyaddition reaction, tailoring their mechanical properties through controlled soft-to-hard segment ratios. MXene layers were successfully deposited onto PU substrates via spin coating, producing flexible strain sensors capable of reliable and reproducible responses to mechanical deformation. In addition, LIG synthesized using direct laser induction on polyimide and subsequent transfer onto optimized PU substrates with 50 wt.% soft segment (PU-50) demonstrated superior pulse-sensing capabilities and improved adhesion. Comprehensive characterization employing cytotoxicity assays, mechanical tests, scanning electron microscopy (SEM), infrarred spectroscopy (FTIR), Raman spectroscopy, and electrical measurements confirmed the good biocompatibility of the substrate, mechanical and structural integrity, functional properties, and high sensitivity of the fabricated sensors. Cytotoxicity assays, employing endothelial cell cultures, verified the biocompatibility of the sensor materials, highlighting their potential in medical and wearable applications. This lecture integrates key findings from recent studies, emphasizing the synthesis, characterization, and performance evaluation of flexible strain and pulse rate sensors using advanced conductive MXene and LIG on biocompatible polymer substrates.
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Thematic field:
SIMPOZIJUM B - Biomaterijali i nanomedicina
Date:
27.05.2025.
Contemporary Materials 2025 - Savremeni Materijali
Paper file
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