NANOMATERIALS AS DRUG CARRIERS FOR CANCER THERAPY

1. Srđan Vuković, Tehnološki fakultet u Istočnom Sarajevu, Republic of Srpska, Bosnia and Herzegovina
2. Danijela Rajić, Tehnološki fakultet Zvornik Univerziteta u Istočnom Sarajevu, Karakaj bb 75400 Zvornik, Republic of Srpska, Bosnia and Herzegovina
3. Svetlana Pelemiš, Tehnološki fakultet u Istočnom Sarajevu, Republic of Srpska, Bosnia and Herzegovina

Cancer is a leading cause of death and poor quality of life globally. Even though several strategies are developed to reduce death, chronic pain and improve the quality of life, there remains a shortfall in the adequacies of these cancer therapies. Among the cardinal steps towards ensuring optimal cancer treatment are early detection of cancer cells and drug application with high specificity to reduce toxicities.
Nanotechnology has the potential to increase the selectivity and potential of chemical, physical, and biological approaches for eliciting cancer cell death while minimizing collateral toxicity to nonmalignant cells. Materials on the nanoscale are increasingly being targeted to cancer cells with great specificity through both active and passive targeting.
The possibility of modifying nanomaterial carriers with more active components enables the delivery of various drugs. Therefore, nanomaterial drug carriers can be organized and optimized for site-specific chemotherapy, thermotherapy, photodynamic therapy, and radiotherapy. In this review recent literature that has broken new ground in the use of nanotechnology for cancer treatment with an emphasis on targeted drug delivery is summarized.

Ključne reči: nanomaterials; cancer; drug carriers; therapy

Tematska oblast: SIMPOZIJUM B - Biomaterijali i nanomedicina

Datum: 06.07.2021.

Contemporary Materials 2021 - Savremeni Materijali


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