1. Gorana Mrđan, Prirodno-matematički fakultet u Novom Sadu, Serbia
2. Đenđi Vaštag, Serbia
3. Suzana Apostolov, Univerzitet u Novom Sadu, Prirodno-matematički fakultet, Serbia
4. Milena Rašeta, Univerzitet u Novom Sadu, Prirodno-matematički fakultet, Departman za fiziku, Serbia
5. Tatjana Verbić, Serbia
6. Olivera Marković, Hemijski fakultet, Univerzitet u Beogradu, Serbia
7. Borko Matijević, Serbia
Carbohydrazones and their thio analogs represent compounds obtained by condensation of carbohydrazide and thiocarbohydrazide with carbonyl compounds. Due to their structure, relatively simple synthesis, and high reactivity, mentioned derivatives have a wide range of applications in all fields. In this study, ionization constants of four newly synthesized mono(thio)carbohydrazones were determined by applying the potentiometric method. Also, the influence of specific and nonspecific intermolecular interactions on maxima shifting in UV-Vis absorption spectra was investigated and quantified using the linear solvation energy relationships method and Catalan’s model. Finally, by applying the DPPH assay, the antioxidant potential of the newly synthesized compounds was determined, and thiocarbohydrazone derivatives proved to be significantly more active when compared to carbohydrazones.
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SIMPOZIJUM B - Biomaterijali i nanomedicina
Date:
02.08.2021.
Contemporary Materials 2021 - Savremeni materijali
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